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Can NAD+ help ease symptoms of perimenopause?

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Plus: Myth-busting aging at Stanford, Allure highlights Cofactor, and The Strategist editors take Basis, daily.
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ELYSIUM
This month, we’re sharing our biggest announcement yet: The Elysium Longevity Institute, a physician-led platform for personalized longevity medicine—and you’re invited to secure your spot on the waitlist. Also in this issue: a pivotal new pilot study from Elysium in collaboration with other researchers found that raising NAD+ with Basis eased some of the most disruptive symptoms of perimenopause—hot flashes, bloating, and disrupted sleep. Plus, Allure recommends Basis, Mosaic, and Cofactor; The Strategist names Basis an essential part of their supplement routine; and Elysium experts discuss emerging biological age research at Stanford’s Healthy Aging 2026 conference.
The Elysium
Longevity Institute | ELYSIUM
For over a decade, Elysium has led the way in commercializing longevity research—from NAD+ to brain aging to biological age, and more. Now, we’re introducing The Elysium Longevity Institute: a physician-led program for personalized longevity medicine. Years in development, The Institute is built on diagnostics and the latest science, designed to provide protocols that maximize healthspan—including personalized prescriptions, injectables, peptides, and more. 

We invite you to join the waitlist now ahead of our summer launch.
Cofactor
Allure recently explored a review of clinical data regarding collagen efficacy, then spoke to board-certified dermatologist Dr. Daniel Belkin on the subject. Dr. Belkin highlighted Elysium’s research-backed approach, which gave him the confidence to recommend our products to his patients—and use them himself. His personal daily routine includes Basis for NAD+ and Mosaic for collagen support. And he recently began using Cofactor, after seeing his patients' success. “My patients are telling me this is helping them,” he said. “Let me try it.”
Join thousands of others already on the waitlist for TELI
HEALTHY AGING 2026
At Stanford’s Healthy Aging conference, Elysium’s Director of Bioinformatics, Rafael Valentin, Ph.D., and Elysium Advisory Board member Michael Fredericson, M.D., tackled a major question: Can we reverse biological aging? Dr. Valentin shared data proving that while chronological age marches on, targeted supplementation can actively reduce the rate of biological aging. In a forthcoming Elysium study, healthy participants taking an NAD+ precursor experienced a decrease in biological age progression compared to those who didn't.* As Dr. Valentin noted, “Not only do we have evidence that you can reverse the effects of aging, but we can even help healthy people reduce it.”
*Compared to individuals who did not take Basis. Biological age can also be influenced by various environmental and lifestyle factors and changes.
A new pilot study from researchers at Elysium Health, Emory University, and the University of South Alabama suggests a non-hormonal path for perimenopause. After just seven days taking Basis (250 mg nicotinamide riboside and 50 mg pterostilbene), more than 75% of symptomatic participants reported improvements in hot flashes, bloating, and sleep.* The study showed Basis increases NADPH, the cofactor required to convert estrone to the more potent estradiol. As study co-author Dr. Marie Migaud explains, Basis safely increases NAD+ and NADPH to “favor the reduction of estrone to estradiol, achieving a more natural approach to addressing symptoms.”
*Based on self-reported changes in symptoms before/after Basis supplementation in 32 women experiencing pre/postmenopausal symptoms.
NAD is like sunscreen—you don't notice it working until you stop.
The Strategist recently went inside the supplement stacks of their beauty and wellness editors—and Basis made the cut. The editors said boosting NAD+ is a little like wearing sunscreen: you may not necessarily "feel" it working in the moment, but you definitely notice when it’s missing. Basis works beneath the surface to support DNA maintenance and energy production. It’s not about a temporary jolt; it’s about maintaining your biological hardware so you stay resilient for the long haul.
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Within 2 weeks, I could definitely see and feel an improvement. That doesn't happen often when taking a new supplement.
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We’d love to hear from you! If you have a story to share about your experience with Elysium products, we want to celebrate your health journey. Please email care@elysiumhealth.com and your story may be featured in an upcoming newsletter or on our social media channels.
 
 
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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease, and are intended for healthy adults, 18 years of age or older. If pregnant or nursing, consult with your physician before using.
 
 

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